大肠癌围手术期中医证候分布及动态变化规律的临床研究

Research on the Distribution and Dynamic Changes of Traditional Chinese Medical Syndromes in Perioperative Patients with Colorectal Cancer

目的:观察大肠癌围手术期中医证候分布及动态变化规律。方法:收集95例大肠癌患者的中医证候信息进行样品聚类统计分析。结果:术前以实证为主,术后以虚证频数逐渐增多,湿热蕴结、气血瘀滞等实证多逐渐演变为气血两虚、脾肾阳虚、肝肾阴虚等虚证。结论:大肠癌的围手术期中医证候术前以实证为主,术后以虚证多见,动态变化特点呈现由实至虚。

Objective:To explore the distribution and dynamic changes of traditional Chinese medical(TCM) syndromes in perioperative patients with colorectal cancer.Methods:TCM syndrome information of 95 colorectal cancer patients was collected and analyzed by sample cluster. Results:Excess syndromes dominated before operation;after operation,the percentages of deficiency syndromes increased,and the syndromes of damp - heat stagnation,Qi - stagnation and blood - stasis developed into deficiency of both Qi and blood,deficiency of spleen and kidney yang,and deficiency of liver and kidney yin gradually.Conclusion:TCM syndromes in perioperative patients with colorectal cancer mainly show as the excess syndromes before operation,and as the deficiency syndromes after operation,presenting the dynamic changes of excess syndrome developing into deficiency syndrome.