摘要
目的:观察脉律康胶囊和阿托品治疗病态窦房结综合征(SSS)的疗效。方法:将280例SSS患者随机分为治疗组(200例)和对照组(80例)。对照组口服阿托品,每次0.3mg~0.9mg,每日3次。治疗组口服脉律康胶囊,每次4粒,每日3次;阿托品每次0.3mg,每日3次。2组重症患者均首先静滴阿托品。2组疗程均为1个月。结果:治疗组治愈116例,好转74例,无效10例,总有效率95.0%;对照组治愈23例,好转36例,无效21例,总有效率73.8%。治疗组总有效率明显高于对照组(χ2=23.20,P<0.01);副反应发生率治疗组(9.0%)显著低于对照组(21.3%,χ2=5.95,P<0.05)。
Objective:To observe the therapeutic efficacy of Mailukang Capsule combined atropin on sick sinus syndrome (SSS).Methods:Patients of SSS (280 cases) were divided randomly into treatment group (200 cases) and control group (80 cases).The control group was treated with oral atropin 0 3 mg ̄0 9 mg every time,3 times daily,while treatment group with oral Mailukang Capsule 4 pills and atropin 0 3 mg every time,3 times daily (atropin intravenous drip primarily in severe case),all 30 days as a therapy course.Results:In treatment group,116 cases were cured,74 cases were improved,10 cases were no changed,the total effective rate was 95 0%;in control group,23 cases were cured,36 cases were improved,21 cases were no changed,the total effective rate was 73 8%;the total effective rate of treatment group was higher obviously than control group (χ 2=23 20, P <0 01);the incidence of sideeffect in treatment group (9 0%) was lower obviously than control group (21 3%;χ 2=5 95, P <0 05).Conclusions:Mailukang Capsule combined atropin treating SSS are effective way.