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干细胞在再生医学领域的临床应用现状及其前景 被引量:19

Clinical application and prospect of stem cells in the field of regeneration medicine
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摘要 干细胞在一定条件下,可以定向分化成机体内的功能细胞,形成任何类型的组织和器官,文章叙述了干细胞与再生医学的概念与分类,探讨了干细胞在糖尿病、心肌细胞损伤性疾病、神经损伤性疾病治疗方面的应用,分析并总结了干细胞与再生医学所面临的问题。分析处理资料显示,干细胞已经广泛应用于心血管系统疾病、神经系统疾病、骨骼肌肉相关疾病,糖尿病等多种疾病的临床试验中,并且取得初步疗效,展示了广泛的临床应用前景。 Stem cells under the controlled condition may directionally differentiate into function cells in organism, formed various types of the organization and the organ. This article narrated the concept and classification of stem cells and regeneration medicine, discussed the application of stem cells to diabetes, myocardial cell damage disease, and neurotrosis disease, analyzed and summarized the problems of stem cells and regeneration medicine. The analysis processing material demonstrated that stem cells have been widely applied to clinical trials addressing cardiovascular system disease, nervous system disease, skeleton muscle related disease, diabetes and so on. This has obtained preliminary curative effect and has demonstrated the widespread clinical practice prospect.
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出处 《中国组织工程研究与临床康复》 CAS CSCD 北大核心 2009年第36期7163-7166,共4页 Journal of Clinical Rehabilitative Tissue Engineering Research
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  • 1Czyz J, Wiese C, Rolletschek A, et al. Potential of embryonic and adult stem cells in vitro. Biol Chem. 2003;384(10-11):1391-1409.
  • 2Shamblott M J, Axelman J, Wang S, et al. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci U S A. 1998;95(23):13726-13731.
  • 3Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282 (5391):1145-1147.
  • 4Chernoff EA, Stocum DL, Nye HL, et al. Urodele spinal cord regeneration and related processes. Dev Dyn. 2003;226(2): 295-307.
  • 5Devendra D, Liu E, Eisenbarth GS. Type 1 diabetes: recent developments. BMJ. 2004;328(7442):750-754.
  • 6Petersen KF, Shulman GI. Etiology of insulin resistance. Am J Med. 2006; 119(5 Suppl 1 ):S10-16.
  • 7Scharp DW, Lacy PE, Santiago JV, et al. Insulin independence after islet transplantation into type I diabetic patient. Diabetes. 1990;39(4):515-518.
  • 8E, randhorst H, Brandhorst D, Brendel MD, et al. Assessment of intracellular insulin content during all steps of human islet isolation procedure. Cell Transplant. 1998;7(5):489-495.
  • 9Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.N Engl J Med. 2000;343(4):230-238.
  • 10Shapiro AM, Ricordi C, Hering B.Edmonton's islet success has indeed been replicated elsewhere.Lancet. 2003;362(9391 ):1242.

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