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英夫利西单抗治疗顽固性克罗恩病并短肠综合征1例

Efficacy of infliximab in treatment of Crohn's disease with short-bowel syndrome: one case report
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摘要 英夫利西单抗有助于防止克罗恩病的复发,是克罗恩病合并短肠综合征者的有效治疗手段,有助于防止剩余小肠受累,提高生活质量。 Infliximah is an effective therapy in patients with Crohn' s disease affiliated short-bowel syndrome, which could induce remission of Crohn' s disease, prevent the remaining small bowel involvement and improve the quality of life.
出处 《胃肠病学和肝病学杂志》 CAS 2009年第9期809-809,813,共2页 Chinese Journal of Gastroenterology and Hepatology
关键词 英夫利西单抗 克罗恩病 短肠综合征 Infliximab Crohn' s disease Short-bowel syndrome
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参考文献4

  • 1Targan SR, Hanauer SB, Van Deventer S J, el al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease [J]. N Engl J Med, 1997, 337(15): 1029-1035.
  • 2Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT 1 randomised trial[J]. Lancet, 2002, 359(9317) : 1541-1549.
  • 3Sands BE, Anderson FH, Bernstein CN, eL al. Infliximab maintenance therapy for fistulizing Crohn's disease [ J]. N Engl J Med, 2004, 350 (9) : 876-885.
  • 4Lees CW, All A, Thompson AI, et al. The safety profile of anti-TNF therapy in inflammatory bowel disease in clinical praclice: analysis of 620 patient-years follow-up[J]. Aliment Pharmacol Ther, 2009, 29 (3) : 286-297.

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