2005-2008年烧伤患者病原菌分布特点及耐药性分析

Burn ward 2005-2008 pathogen distribution and drug resistance analysis

目的研究近4年烧伤患者病原菌分布及耐药状况。方法对本单位2005年1月～2008年12月住院烧伤患者的细菌培养及药物敏感试验结果进行了回顾性分析。结果革兰阳性球菌139株(41.74%),分离率最高的为金黄色葡萄球菌(30.33%),其中耐甲氧西林金黄色葡萄球菌(MRSA)的分离率较高(67.33%);革兰阴性杆菌194株(58.26%),分离率最高的为铜绿假单胞菌(21.92%);革兰阴性菌对第三代头孢菌素和氨基糖苷类耐药率有较显著增加。结论烧伤惠者临床标本中分离细菌耐药问题严重,应加强耐药性监测和临床对抗菌药物使用的管理制度,以有效控制细菌感染和耐药性的播散。

Objective To investigative the past 4 years the distribution of burn patients and drug resistance of pathogenic bacteria. Methods Approach to this unit from January 2005 to December 2008 hospitalized bum patients with bacterial culture and drug susceptibility test results were analyzed retrospectively. Results The outcome of gram-positive cocci 139 （41.74%）, the highest rate for the separation of Staphylococcus aureus （30.33%）, in which methicillin-resistant Staphylo-coccus aureus （MRSA） separation rates are relatively high （67.33%）; Gram negative bacilli in 194 （58.26%）, separation of the highest rates for Pseudomonas aeruginosa （21.92%）; Gramnegative bacilli to third generation cephalosporins and aminoglycoside resistance rates increa- sed significantly more. Conclusion of clinical specimens of patients with burns isolated problem of bacterial resistance should be strengthened to monitor drug resistance and clinical use of antibacterial drugs management system to effectively control the bacterial infection and the spread of drug resistance.