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颈动脉粥样硬化斑块的磁共振成像特点 被引量：2

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摘要 影像学检查在缺血性卒中的诊治、预后评估中的价值毋庸置疑。随着以"病人为中心"、在循证医学基础之上的个体化医疗观念的不断深入,临床对影像学检查的要求也越来越高。在急性缺血性卒中的影像学检查中,准确、快捷是首要的;而对非急性缺血性卒中而言,准确和全面则是下一步治疗和预防的基础。本期的几篇研究论文对此进行了初步的尝试。基于磁共振成像(magnetic resonance imaging,MRI)表观弥散系数(apparent diffusion coefficient,ADC)对急性缺血性卒中梗死核心以及缺血半暗带的研究,摒弃了传统的MRI灌注加权像(perfusion-weighted imaging,PWI)和弥散加权像(diffusion-weighted imaging,DWI)不匹配模型的作法,省却了PWI的检查,仅仅对DWI和ADC的数据进行分析,获取梗死核心和缺血半暗带,大大简化了急诊状态下的MRI程序,缩短了检查时间,显示出广阔的临床应用前景。基于磁共振血管成像(magnetic resonance angiography,MRA)的颈动脉分叉血流动力学研究,从计算机模拟上升到在体测量,使得靶血管局部血流动力学的研究更贴近临床,为临床进一步认识动脉粥样硬化斑块的转归建立了切实可行的影像技术平台。毛细血管表面通透性的影像学研究为临床预测缺血性卒中静脉溶栓治疗后的出血转化提供了一个切实可行的技术方法。可以说,临床与影像的紧密结合使得影像学研究更具生命力。
作者 荆利娜 高培毅
机构地区 首都医科大学附属北京天坛医院神经影像中心
出处 《中国卒中杂志》 2009年第9期757-761,共5页 Chinese Journal of Stroke
关键词 颈动脉狭窄 磁共振成像
分类号 R743 [医药卫生—神经病学与精神病学] R445.2 [医药卫生—影像医学与核医学]
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参考文献11

  • 1于风旭,邓明彬,陈槐卿,石应康,廖斌,李新.人颈动脉分叉模型流场分布的数值模拟[J].第三军医大学学报,2007,29(24):2336-2338. 被引量：4
  • 2Gorellick PB,Sacco RL,Smith DB,et al.Prevention of a first stroke:a review of guidelines and a multidisciplinary consensus statement from the National Stroke Association[].JAMR.1999
  • 3Balu N,Chu BC,Hatsukami TS.Comparison between2D and3D high-resolution black-blood techniques for carotid artery wall imaging in clinically significant atherosclerosis[].Magnetic Resonance Imaging.2008
  • 4Balu N,Chu BC,Hatsukami TS.Comparison between2D and3D high-resolution black-blood techniques for carotid artery wall imaging in clinically significant atherosclerosis[].Magnetic Resonance Imaging.2008
  • 5Naghavi M,Libby P,Falk E,et al.From vulnerable plaque to vulnerable patient:a call for new definitions and risk assessmentstrategies--partⅡ[J].Circulation,2003,108:1772-177812Saam T,Ferguson MS,Yarnykh VL,et al.Quanti-tative evaluation of carotid plaque composition by in vivo MRI[].Arteriosclerosis and Thrombosis.2005
  • 6Boyd J,Buick JM.Three-dimensional modelling of the human carotid artery using the lattice Boltzmann method:Ⅱshear analysis[].Physics in Medicine and Biology.2008
  • 7Li ZY,Taviani V,Gillard JH.The impact of wall shear stress and pressure drop on the stability of the atherosclerotic plaque[].Conf Proc IEEE Eng MedBiol Soc.2008
  • 8Box FM,Grond J,Craen A,et al.Pravastatin decreases wall shear stress and blood velocityin the internal carotid artery without affecting flow volume:results from the PROSPER MRI study[].Stroke.2007
  • 9Clarke SE,Hammond R R,Mitchell JR.Quantitative Assessment of Carotid Plaque Composition Using Multicontrast MRI and Registered Histology[].Magnetic Resonance in Medicine.2003
  • 10Saam T,Ferguson MS,Yarnykh VL,et al.Quantitative evaluationof carotid plaque composition byin vivoMRI[].Arteriosclerosis Thrombosis and Vascular Biology.2005

二级参考文献13

  • 1Caro C G,Fitz-Gerald J M,Schroter R C. Arterial wall shear and distribution of early atheroma in man [ J ]. Nature, 1969, 223 (5211 ) : 1159 -1160.
  • 2Caro C G, Fitz-Gerald J M, Schroter R C. Atheroma and arterial wall shear. Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis[ J]. Proc R Soc Lond B Bid Sci, 1971, 177(46) : 109 - 159.
  • 3Box F M, van-der-Geest R J, Rutten M C, et al. The influence of flow, vessel diameter, and non-newtonian blood viscosity on the wall shear stress in a carotid bifurcation model for unsteady flow[ J]. Invest Radiol, 2005, 40(5): 277-294.
  • 4Jo H, Song H, Mowbray A. Role of NADPH oxidases in disturbed flow- and BMP4- induced inflammation and atherosclerosis [ J ]. Antioxid Redox Signal, 2006, 8(9 -10) : 1609 -1619.
  • 5Han Z, Chen Y R, Jones C I, 3rd. ,et al. Shear-induced reactive nitrogen species inhibit mitochondrial respiratory complex activities in cultured vascular endothelial cells [ J ]. Am J Physiol Cell Physiol, 2007, 292(3) : C1103 -C1112.
  • 6Ding Z, Wang K, Li J, et al. Flow field and oscillatory shear stress in a tuning-fork-shaped model of the average human carotid bifurcation [J]. J Biomech, 2001, 34( 12): 1555 -1562.
  • 7Friedman M H, Deters O J, Mark F F, et al. Arterial geometry affects hemodynamics. A potential risk factor for atherosclerosis [J]. Atherosclerosis, 1983,46(2) : 225 -231.
  • 8Slager C J, Wentzel J J, Gijsen F J, et al. The role of shear stress in the generation of rupture-prone vulnerable plaques [ J ]. Nat Clin Pract Cardiovasc Med, 2005, 2(8) : 401 -407.
  • 9Zarins C K, Giddens D P, Bharadavaj B K, et al. Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress[J]. Circ Res, 1983, 53 (4) : 502 -514.
  • 10Zhao S Z, Ariff B, Long Q, et al. Inter-individual variations in wall shear stress and mechanical stress distributions at the carotid artery bifurcation of healthy humans[J]. J Biomech, 2002, 35( 10): 1367-1377.

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中国卒中杂志
2009年 第9期

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