复方龟鹿颗粒剂对失血性贫血小鼠的补血作用

Antanemic Effect of Compound Guilu Granule on Hemorrhagic Anemia Mice

目的比较复方龟鹿颗粒剂与膏剂对失血性贫血小鼠的补血作用。方法用断尾取血法造成失血性贫血小鼠模型,观察复方龟鹿颗粒剂与膏剂对小鼠的红细胞数、白细胞数、血小板及血红蛋白含量的影响。结果造模可使小鼠红细胞数、白细胞和血小板数减少、血红蛋白含量降低。给予不同剂量的复方龟鹿颗粒剂及膏剂后,红细胞数、白细胞数、血小板和血红蛋白含量均明显升高,复方龟鹿颗粒高剂量组最为显著。结论复方龟鹿颗粒剂补血作用同膏剂相当,且其应用范围更广。

Objective： To compare the effect between the granule and the paste of the Compound Guilu on hemorrhagic anemia mice. Methods： The model of hemorrhagic anemia was established by collecting blood from docking method. The erythrocyte, the leukocyte, the platelet and the content of the hemoglobin were determined. Results： These indices above were decreased in mice models. After being used several dose of Compound Guilu Granule and Paste, these indices were ascended significantly. The effect was the most obvious in the group of high dose Compound Guilin Granule. Conclusion： Compound Guilu Granule has larger application range although its effect is equivalent to the paste.