经脐静脉导管采集血液标本化验的可行性研究

The feasibility study of collecting blood specimen from umbilical vein catheter for blood determination

目的探讨从脐静脉导管采集血液标本化验的可行性和正确采血方法。方法将留置脐静脉导管的80例早产儿随机分成采血组和非采血组各40例，比较两组导管相关并发症和不良反应。采血组40例在暂停输液30s后先抽出一定量的血液（观察1组2ml、观察2组4ml）再采血标本，对照组同时在外周血管穿刺采血标本，检测3组标本的血常规、血生化、肝功能并对结果进行分析比较。结果观察1组、观察2组与对照组检测结果差异无统计学意义；采血组和非采血组脐静脉导管并发症发生率差异无显著性（P〉0．05）。结论观察1组采血法即在脐静脉导管暂停输液30S后先抽出血液2ml再采血检验对结果影响不明显；脐静脉导管采血对导管正常使用无明显影响，具有无痛苦、成功率高、可反复采集等优点，可作为NICU采集血标本的途径之一。

Objective To investigate the feasibility of collecting blood specimen from umbilical vein catheter for blood determination. Methods 80 premature infants that indwelling catheter were divided into drawing blood and non - drawing blood groups, then the interrelated complicating disease and adverse reaction between the two groups were compared. First blood was drawn in definite quantity from 40 premature infants in the drawing blood group 30s after suspending transfusion, then blood specimen was collected （observational group one 2ml, observational group two 4ml ） . While blood specimen in control group was collected by puncturing peripheral blood vessel. At last the blood routine test, biochemistry and liver function in the three groups were tested to analyze and compare the results. Results There was no statistical significance in the discrepancy of the test results among the three groups. There was no significance in the discrepancy of the incidence rate of umbilical venous catheter complication between drawing blood group and non - drawing blood group （P 〉 0. 05） . Conelusions The method of drawing 2ml blood 30s after suspending transfusion from umbilical venous catheter and then exsanguina- ring to test has no obvious infection on the result. Collecting blood from umbilical venous catheter has no obvious infection on regular service of the catheter and it possesses the advantage of being no complaints, high success rate and exsanguinating repeatedly. So it can be used one of the way to collect blood specimen.