医院感染肠球菌的分布特点及其药敏分析

The rule of distribution and drug-sensitivity test by Enterococcus in nosocomial infection

目的了解医院感染肠球菌的分布特点及其药敏情况，供临床参考。方法对2007年9月至2008年12月期间，从各临床科室送检标本中分离到的肠球菌223株进行分析与药敏实验。结果分离到的肠球菌中，粪肠球菌和尿肠球菌分离率最高，分别是68．24％和26．61％，分离出肠球菌最多的标本是尿液、痰和胆汁，分别是88株、45株和36株，粪肠球菌和屎肠球菌对万古霉素敏感率最高达97．48—98．38％，其次呋喃妥因和氨苄西林，敏感率在53．23～84．27％，对环沙星和氧氟沙星6种抗生素敏感率在24．50～53．22％。结论医院感染肠球菌以泌尿道和呼吸道最为常见，感染的肠球菌对常用抗菌素耐药性高，且呈多重性耐药，并已出现对万古霉素不敏感株，应引起关注。

Objective To investigate and find the rule of site distribution by Enterococcus in nosocomial infection,and the offer the referrence to clinic. Methods 223 Enterococcus strains were different infection specimens in the hospital from September 2007 to December 2008 were analyzed and performed the drug-sensitivity test. Results In the 223 isolated Enterococeus strains, the isolation rates of E. faeealis and E. faecium were 68.24% and 26. 61%. The specimen type with most isolation rates of Enterococcus were urine,sputum and bile, with the number 88 strains ,45 strains and 36 strains. In the drug-sensitivity test, E. faecalis and E. faecium were sensitized to,with the rate from 97.48% to 98. 38%. The drug-susceptibility rates of Enteroeoccus to nitrofurantoin and ampiciMn were from 53.23% to 84. 27%. The drug-susceptibility rates of Enterococcus to ciprofloxacin and Ofloxacin were from 24. 50% to 53.22%. Conclusion Enterocoeeus isolated from nosocomial infection were heavily resistanted to antibiotics and multi-drug resistant. And some Enteroeoccus strains became resistanted to vancomycin. All above should be paid more attention to.