1036例消化性溃疡症状学聚类研究

Cluster Analysis on Semeiology in Peptic Ulcer,A Report of 1036 Cases

目的:探讨消化性溃疡的症状组合规律和证候规律。方法:采用临床流行病学的原则和方法,应用系统聚类的方法对大样本病例的症征进行分析研究。结果:采用聚类分析研究,得出消化性溃疡基本中医证候为五类:脾胃虚寒证、肝胃气滞证、瘀阻胃络证、胃热炽盛证、胃阴亏虚证。结论:聚类结果与PU中医临床辨证分型基本相符。聚类分析统计方法对症状组合规律、证候规律等方面的研究具有确定性意义。

Objective：To investigate the grouping law of symptoms and syndrome law in peptic ulcer. Method： According to the principle of clinical epidemiology and its method, the author analyzed and studied the symptoms of peptic ulcer in large sample by cluster analysis. Result ： The basic TCM syndromes of peptic ulcer could be summed up into five categories, which were syndrome of insufficiency of spleen-yang, syndrome of stagnation of liver-qi and stomach-qi, syndrome of the stasis blocking the collaterals in the stomach, syndrome of gastric heat flaming, and syndrome of deficient fluid in stomach. Conclusion ： The result of cluster analysis is the same as TCM clinical differentiation of symptoms and signs for classification of syndrome. Statistical method of cluster analysis has important significance on the study of the grouping law of symptoms and syndrome law.