从分子生物学探索食管癌辨证分型的基本策略

Basic-tactics on Dialectical Typing of Esophageal Cancer from Molecular Biology

中医临床将食管癌辨证为痰气交阻、痰瘀互结、津亏热结、气虚阳微4型,考虑以分子生物学技术从与食管癌的痰、瘀、气、阴、阳相关基因入手,通过大样本,比较其在与证相关的分子生物学领域的差异性,为食道癌的辨证分型提供科学的参考依据,指导临床用药和药物作用机制的探讨。

Abstract： Esophageal cancer is differentiated into tan and qi interlaced, tan and haemostasis combinated, body flu- ids deficiency and accumulation of heat,qi deficiency accompanied with yang decadency by TCM. Difference between patterns of syndrome might be studied related gene include tan, haemostasis, qi, ying and yang in large sample by protocols in molecular biology. It is referred value to different patterns of esophageal cancer and instructed clinical medication, and to study mechanism of drug action.