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宫颈液基不满意标本对宫颈病变检出率的影响 被引量:1

Influence of Unsatisfactory Thinprep Samples on Cervical Lesion Detection Rate
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摘要 目的评价不满意标本对病变检出率的影响。方法选择13205例行新柏氏液基细胞学宫颈检查病例,将其中的1770例不满意标本用冰醋酸进行重新处理,对重处理仍不满意者重新取材,至制片满意后再次判读。结果重新处理后,不满意率由13.4%下降到1.43%,下降了11.97%。重处理组与标本满意未处理组比较病变检出率无显著性差异,但高度病变以上的检出率重处理组有大于未处理组的趋势。重取材组各级别病变检出率均显著高于重处理组和未处理组(P<0.05)。结论宫颈病变可导致液基细胞学取材制片不满意率增加,应重视对不满意标本的重新处理或重取材,提高宫颈病变的检出率。 Objective The effect of unsatisfactory ThinPrep samples on lesion 's detection rate was evaluated. Methods Total 1770 unsatisfactory ThinPrep samples out of 13205 samples were selected. They all were reproeessed by glacial acetic acid. If reprocessed unsuccessfully , they were renewed. Results After reprocessed, the unsatisfactory rate declines from 13.4% to 1.43% , 11.97% reduction. There' s no significant difference between the reprocessed group and control group on lesion detection rate. The rate of above HSIL in reprocessed group was higher than that in control group, but it's not significant. In renewed group, the rate of all grade lesion were higher than that in reprocessed group and control group ( P 〈 0. 05 ). Conclusion Cervical lesions can increase the rate of unsatisfactory slides. It should be paled more attention to the reprocessing or renewing of unsatisfactory ThinPrep samples so that the detection rate of lesion in cervical can be raised.
出处 《医药论坛杂志》 2009年第18期34-37,共4页 Journal of Medical Forum
关键词 液基细胞学 子宫颈上皮内瘤变 检验 Liquid - based Cytology Cervical intraepithelial neoplasia Detection
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参考文献10

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共引文献6

同被引文献10

  • 1Nance K V.Evolution of pap testing at a community hospital-a ten year experience. Diagnostic Cytopathology . 2007
  • 2Islam S,West A M,Saboorian M H,et al.Reprocessingunsatisfactory ThinPrep papanicolaou test specimens increa-ses sample adequacy and detection of significant cervicovagi-nal lesions. Cancer . 2004
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  • 8韦荣干,卢军营,韦玉霞.宫颈液基血液或炎细胞过多标本处理后制片效果评价[J].广西医学,2010,32(4):427-429. 被引量:4
  • 9黄思毅,刘芳芳.液基细胞学联合阴道镜检查在诊断宫颈病变中的临床价值[J].河北医学,2011,17(3):355-358. 被引量:10
  • 10崔浩杰,易有峰,王晓娟,陈有元.毛细式液基细胞学薄层染色技术对宫颈癌筛查应用价值的探讨[J].中华肿瘤防治杂志,2011,18(2):142-143. 被引量:17

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