万古霉素脑室内灌注治疗儿童脑室感染

Intraventricle perfnsion of vancomycin for the treatment of ventricle inflammation in enfants

目的探讨儿童脑室感染的易患因素与治疗措施。方法回顾性分析80例儿童脑室系统肿瘤、脑积水术后的临床资料，分析脑室感染的易患因素及有效的治疗方法。结果80例患者中发生脑室感染9例，发生率为11．25％，均采用脑室内万古霉素灌洗持续引流治疗及全身合理使用有效抗生素，收到良好效果，9例全部治愈。结论脑室外引流是脑室感染的主要原因之一，严格的术中无菌操作及术后脑室外引流时限的控制，以及换药处置时严格的无菌操作，可减少脑室感染的发生，万古霉素脑室内灌洗持续引流是治疗脑室感染的有效措施。

Objective To explore the risk factors of ventricle inflammation in eufants and its treatment. Method Clinical data about 80 infants suffering ventricle tumors and post operative waterhead were collected for the analysis of the risk factors of ventricle inflammation and its effective therapeutic methods. Results 9 cases were diagnosed as ventricle inflammation, accounting for 11.25% of the total cases. Continuous intraventricle drainage of vancomycin and systemic application of efficacious antibiotics were undertaken in all of these 9 cases, all of whom were cured, proving effective. Conclusions Extraventricle drainage represents the main reason for ventricle inflammation, and strict asepsis during operation and postoperative medication renewal of incision, restricting drainage time can reduce the onset of ventricle inflammation. Continuous intraventricle drainage of vancomycin represents one of the effective therapeutic methods for the treatment ventricle inflammation.