摘要
本实验拟研究精制蜂胶对小鼠免疫功能的影响。采用45、90、135mg/kgbw剂量的精制蜂胶给小鼠经口灌胃30d,分别测定免疫器官脏器/体重比值,进行迟发型变态反应、ConA诱导的小鼠淋巴细胞转化实验、抗体生成细胞检测、半数溶血值测定、小鼠碳廓清实验和NK细胞活性的测定。结果发现:与阴性对照组比较,135mg/kgbw剂量能明显提高小鼠的迟发型变态反应的能力,能明显提高胸腺体重比值、小鼠抗体生成细胞数、半数溶血值,明显增强小鼠单核-巨噬细胞碳廓清能力,明显提高小鼠NK细胞活性,证明精制蜂胶具有潜在增强免疫力的作用。
In order to study the effects of refined propolis on immune function of normal mice, spleen/body and thymus/body weight ratios, delayed type hypersensitivity （DTH）, lymphocyte transformation capacity induced by CortA, antibody forming spleen cells （AFPC）, 50% hemolytic concentration and carbon clearance ability, NK cell activity were determined after mice were orally administered with refined propolis at doses of 45, 90 and 135 mg/kg, bw for 30 days. Compared with the control group, refined propolis at dose of 135 mg/kg.bw could significantly enhance thymus/body weight ratio, DTH; increase and HC50, carbon clearance capacity of mononuclear-macrophages, NK cell activity and lymphocyte transformation capacity induced by ConA in mice. These results indicate that refined propolis can improve immune function in mice.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2009年第19期286-290,共5页
Food Science
关键词
精制蜂胶
脏器体重比值
碳肌酸清能力
NK细胞活性
免疫功能
refined propolis
thymus/body weight ratio
carbon clearance ability
NK cell activity
immune function
