苯并单氮杂15-冠-5与α,β-不饱和羰基化合物的Michael加成

Michael Addition of Monoazabenzo-15-C-5 with Acrylic Esters and Amides

本文报道借Ｍｉｃｈａｅｌ加成使苯并单氮杂１５－冠－５与α，β－不饱和羰基化合物反应，合成了氮支套索冠醚和酯型双冠醚，并提供了合成酯型双冠醚的一种方法，该法条件温和，操作简便，收率高。产物均经ＩＲ，＾１Ｈ ＮＭＲ和ＭＳ 鉴定。

N - Pivot azacrown ethers(1,2) and biscrown ethers(3,4) were synthesized by Michael addition of monoazabenzo - 15 - C - 5 with acrylic esters and amides. A simple and convenient method for preparing biscrown ethers in high yield was provided. All these compounds were indentified by IR, 1H NMR, and MS.