癌痛患者芬太尼透皮贴剂处方剂量影响因素的研究

Study on factors affecting prescription dose of Fentanyi Transdermai Patch for treatment on caner-pain patients

目的了解癌痛患者使用芬太尼透皮贴剂处方剂量的影响因素，为居家宁养护理中正确给予镇痛治疗提供依据。方法对居家宁养的100例中、重度疼痛的癌症患者使用芬太尼透皮贴剂镇痛，以患者不感觉疼痛为准，观察疼痛程度、疼痛部位、性别、年龄与用药剂量的关系。结果重度疼痛患者的维持剂量高于中度疼痛患者，而不同疼痛部位、性别、年龄患者的维持剂量差异无统计学意义。结论疼痛程度是唯一影响芬太尼透皮贴剂处方剂量的因素，实施镇痛治疗时应首先加以考虑。

Objective To analyze the factors affecting prescription dose of Fentanyl Transdermal Patch for treatment on caner-pain patients, and to provide a basis for correctly giving ease pain treatment in peaceful recuperation and nursing. Methods For 100 cases with moderate or severe cancer pain who stayed in home for a peaceful recuperation, fentanyl transdermal patch was used to ease their pains. The relationship betweem pain degree, pain region, sex and age, and the administration dose was observed, taking the patients not feeling pain as the standard. Results The maintaining dose for patients with severe cancer pain was higher than that for patients with moderate cancer pain. But, there was no statistical meaning for the differences on maintaining doses in terms of pain region, sex and age. Conclusions Pain degree is the unique factor affecting close of fentanyl transdermal patch, and should be firstly considered when applying treatment of easing pain.