儿童股骨头缺血坏死的治疗现状与展望

Avascular necrosis of femoral head in children:the status and outlook

儿童股骨头缺血坏死是发生在儿童股骨头局部的自愈性、自限性的非系统性疾病。目前的保守治疗及手术治疗方法较多,主要目的是改善股骨头血循环,降低骨内压和关节内压,减少对股骨头的机械压迫,增加对股骨头的包容。但无论如何治疗均无法阻止患儿成年后出现扁平髋畸形和髋关节退行改变,导致髋关节功能障碍。自体骨髓干细胞移植治疗股骨头坏死已取得初步的疗效,与组织工程骨的联合应用,为儿童股骨头缺血坏死的治疗提供了新的治疗方案。

Children avascular necrosis of femoral head is a self - healing, self - limiting and non - systematic disease oc- eouring locally in femoral head of children. The purpose of traditional conservative and surgical treatments is to improve blood circulation, decrease intraosseous pressue, decrease arthrosis pressure, reduce capital mechanical pressure to the femoral head and increse its containment. Anyway, no treatment could stop the progress of coxa plana and degeneration of the bone, which could lead to disorder of the hip. As a new technique, autologous bone marrow stem cellular transplantation has obtained prelimi- nary curative effect. It has been proved to be a new effective treatment of children avscular necrosis of the femoral head with com- bined use of tissue enginering bone.