68例医院获得性鲍曼不动杆菌肺炎的临床特点及耐药情况分析

Clinical features and the drug resistance in 68 cases of hospital acquired pneumonia caused by Acinetobacter baumannii

目的:了解医院获得性鲍曼不动杆菌肺炎的临床特点及耐药情况。方法:回顾性分析68例医院获得性鲍曼不动杆菌肺炎患者的临床资料。结果:医院获得性鲍曼不动杆菌肺炎以老年人和合并有基础疾病的患者多见,临床表现不存在特异性,常见症状为发热(85.3%)、咳嗽(79.4%)和咳痰(70.6%)。对鲍曼不动杆菌敏感率>60%的抗生素分别是多黏菌素B(85.3%)、米诺环素(69.1%)和亚胺培南/西司他丁(61.8%)。结论:多黏菌素B、米诺环素及亚胺培南/西司他丁是治疗医院获得性鲍曼不动杆菌肺炎较有效的抗生素。

Objective To investigate clinical features and the drug resistance of hospital acquired pneumonia caused by Acinetobacter baumannii. Methods The clinical data and drug sensitivity were studied retrospectively in 68 patients with hospital acquired pneumonia caused by Acinetobacter baumanii. Results Hospital acquired pneumonia caused by Acinetobacter baumannii often occurred in senile patients and those complicated with other diseases, and it had no specific clinical features. Its common symptoms included fever （85. 3%）, cough （79. 4%） and productive cough （70. 6%）. The antibiotics with the sensitivity rate over 60% to Acinetobacter baumannii were polymyxin B （85.3%）, minocycline （69. 1%） and imipenem/cilastatin （61. 8%）. Conclusion The most commonly recommended antibiotics for hospital acquired pneumonia caused by Acinetobacter baumannii are polymyxin B, minocyeline and imipenem/cilastatin.