Eu^(3+)和Al^(3+)离子对DPPC人工膜脂双层主相变温度的影响

Studies on the Influence of Eu 3+ and Al 3+ Ions to the Temperature of the Gel to Liquid crystalline of DPPC Bilayer

天然生物膜组成复杂，直接用于研究困难较大．由于天然生物膜中脂分子的行为与人工脂双层膜的行为十分类似，故我们用单一磷脂制备人工脂双层膜来研究金属离子对其主相变温度的影响．膜的动力学性质依靠膜平面内的液体环境，决定膜流动性的膜成分是磷脂分子．磷脂的重要性...

The experimental data on FTIR and NMR spectra show that the interaction of Eu 3+ and Al 3+ ions with DPPC bilayer can alter the temperature of the gel to liquid crystalline phase transition of DPPC bilayer (increase of about 3 ℃). It can be found that Eu 3+ ion binding to DPPC bilayer makes the radius of DPPC bilayer small, while Al 3+ ion binding to DPPC bilayer makes it large. The complex reaction of Eu 3+ and Al 3+ ion with DPPC bilayer leads to a structual change of the polar head group in DPPC bilayer.