含2-氯-5-吡啶甲基的双氰基取代乙烯酮缩胺类化合物的合成及生物活性

Synthesis and Biological Activity of Biscyano Substituted Acyclic Ketene Aminals Containing 2 Chloro 5 pyridylmethyl Group

新烟碱类杀虫剂由于具有高效、低毒、无交互抗性和内吸性等特点，成为杀虫剂领域新的研究热点［１］．本文以Ｎｉｔｅｎｐｙｒａｍ为母体，首次合成了２－氰基－３－（２－氯－５－吡啶甲氨基）－３－甲硫基丙烯腈（９），并以其为中间体合成了１９个双氰基取代的含２－氯...

In this paper, 2 cyano 3 (2 chloro 5 pyridylmethyl)amino 3 methylthioacrylonitrile 9 was synthesized. By the reaction of 9 as an intermediate with amines, nineteen new biscyano substituted acyclic ketene aminals containing 2 chloro 5 pyridylmethyl group were prepared. When 9 reacted with hydrazine, the corresponding cyclic compounds 10p was obtained. Preliminary bioassays show that 9 has a potential activity against aphid and the compounds 10a, 10f, 10g and 10r in this series have a good herbicidal activity.