摘要
他汀类药物具有肯定的降脂作用,已作为冠状动脉粥样硬化性心脏病的二级预防用药。大量研究显示,他汀类药物还具有除降脂之外的抑制炎症反应、抗心室重塑、改善神经体液调节、抗心律失常、改善血管内皮功能、抗氧化等作用。本文对他汀类药物治疗急性冠脉综合征的临床依据和可能的机制作一综述。
Statins plays a role in reducing blood LDL cholesterol, acting as a second-level prevention drug for coronary artery disease. Many studies have shown that Statins have many other contributions to anti-inflammation, anti-ventricular remodeling, anti-arrhythmia, anti-oxidation and improvement of neurohumoral regulation and endothelial function besides their effect on blood fat decrease. This paper aims to investigate the clinical basis and possible mechanisms for Statins in the treatment of acute coronary syndromes.
出处
《中国医药导报》
CAS
2009年第29期5-6,共2页
China Medical Herald
