期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus （A/HIN1）？ 被引量：6

Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus （A/HIN1）？
下载PDF
导出
摘要 Dear Editor, The current flu epidemic caused by influenza A H1N1 （A/H1N1） virus, which first appeared in Mexico emerged as a communicable human disease in late March and rapidly spread throughout the world in April 2009. Due to the rapid transport systems in modern times, the epidemic affected about 121 countries in less than 4 months （http：//www.who.int/csr/don/2009_07_16/en/）.
作者 Kunqian Yu Cheng Luo Guangrong Qin Zhijian Xu Ning Li Hong Liu Xu Shen Jianpeng Ma Qinghua Wang Caiguang Yang Weiliang Zhu Hualiang Jiang
机构地区 Drug Discovery and Design Center Department of Biochemistry and Molecular Biology School of Pharmacy
出处 《Cell Research》 SCIE CAS CSCD 2009年第10期1221-1224,共4页 细胞研究（英文版）
关键词 甲型流感病毒 禽流感疫情 快速运输系统 人类疾病 http 传染病 墨西哥
分类号 S855.3 [农业科学—临床兽医学] F326.3 [经济管理—产业经济]
  • 相关文献

参考文献15

  • 1Alexander DJ. An overview of the epidemiology of avian influenza. Vaccine 2007; 25:5637-5644.
  • 2Skeik N, Jabr FI. Influenza viruses and the evolution of avian influenza virus H5N1. IntJInfectDis 2008; 12:233-238.
  • 3Taubenberger JK, Reid AH, Lourens RM, et al. Characterization of the 1918 influenza virus polymerase genes. Nature 2005; 437:889-893.
  • 4Tumpey TM, Maines TR, Hoeven NV, et al. A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science 2007; 315:655-659.
  • 5Russell RJ, Haire LF, Stevens D J, et al. The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design. Nature 2006; 443:45-49.
  • 6Mishin VP, Hayden FG, Gubareva LV. Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors. Antimicrob Agents Chemother 2005; 49:4515-4520.
  • 7Mitrasinovic PM. On the structure-based design of novel inhibitors of H5N1 influenza A virus neurarninidase (NA). Biophys Chem 2009; 140:35-38.
  • 8Wade RC. 'Flu' and structure-based drug design. Structure 1997; 5:1139-1145.
  • 9Rameix-Welti MA, Enouf V, Cuvelier F, et al. Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir. PLoS Pathog 2008: 4:e1000103.
  • 10Mihajlovic ML, Mitrasinovic PlVl. Another look at the molecular mechanism of the resistance of H5N1 influenza A virus neuraminidase (NA) to oseltamivir (OTV). Biophys Chem 2008; 136:152-158.

同被引文献76

引证文献6

二级引证文献22

Cell Research
2009年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部