红椿不同提取物药理活性初探

Preliminary Study on Pharmacological Activities of Different Extracts from Toona ciliata

采用无创血压测量技术和医学图像分析技术检测红椿4种不同萃取物对正常大鼠血压及肠系膜微循环的血管管径、血液流速和血流量的影响。结果表明,红椿的乙醇萃取物、石油醚萃取物和氯仿萃取物都有显著升高血压、缩小微循环毛细血管管径、降低血液流速和血流量的作用,其中氯仿萃取物的作用最显著;较高浓度的红椿水提物具有显著降低血压、舒张微循环毛细血管管径,增大血液流速和血流量的作用。

The effects of 4 kinds of extracts from Toona ciliata on blood pressure of normal rats and the vascular caliber, blood velocity, blood flow in their mesenteric microcirculation were studied by techniques of non-invasive blood pressure measurement and medical image analysis technique. The results showed that the ethanol extract, petroleum ether extract and chloroform extract from T. ciliata all had the effects of significantly increasing blood pressure and decreasing diameter of capillary, blood velocity and blood flow, and the effect of chloroform extract was the most obvious. Aqueous extract from T. ciliata with high concn, had the effects of significantly decreasing blood pressure, relaxing diameter of capillary, increasing blood velocity and blood flow.