我院门诊抗高血压药应用情况及趋势分析

Outpatient Use and Tendency of Antihypertensive Drugs in Our Hospital

目的:了解我院门诊抗高血压药的应用情况及趋势。方法:采用回顾性调查方法,抽取我院2007年11月18日～12月17日门诊高血压患者处方952张,统计其用药情况及治疗方案、药品销售金额、用药频度(DDDs)与日均费用(DDC)等。结果:治疗方案中以单一用药和二联用药居多。钙离子拮抗药(CCB)和血管紧张素Ⅱ受体拮抗药(ARB)应用最多,分别占30.67%和28.45%。DDDs排序列前3位的是替米沙坦、氨氯地平、贝尼地平;销售金额排序列前3位的是替米沙坦、缬沙坦和氨氯地平。结论:我院抗高血压药应用基本符合《中国高血压防治指南》及世界卫生组织的用药准则。

OBJECTIVE： To investigate the application situation and tendency of antihypertensive drugs in our hospital. METHODS： By a retrospective study, a total of 952 prescriptions of outpatients with hypertension were sampled from our hospital from Nov. 18 to Dec. 17 in 2007 for statistical analysis regarding the utilization of antihypertensive drugs, the treatment regimens, sales amount, DDDs and DDC, etc. RESULTS： The antihypertensive drugs were mainly used in single or two kinds concomitantly. Calcium-channel blocker （CCB） and angiotensin receptor Ⅱ binders（ARB） took the lead, accounting for 30.67% and 28.45%, respectively. Leading the first three places on the list of DDDs were Telmisartan, Amlodipine and Benidipine, and leading the first three places on the list of sales amount were Telmisartan, Valsartan and Amlodipine. CONCLUSION：The use of antihypertensive drugs in our hospital conforms to China Guidelines on Prevention and Management of Hypertension and the drug use criteria recommended by WHO.