甘油糖脂生物活性最新研究进展

Research Progress on Bioactivities of Glycoglycerolipids

综述了甘油糖脂在生物活性及构效关系方面的研究进展。甘油糖脂是细胞膜的重要组成部分,具有抗氧化、抗病毒、抗菌、抗肿瘤、抗炎、抗动脉粥样硬化等多种生物活性。构效关系的研究表明甘油糖脂的活性与糖脂上脂酰基链的长短、糖环上的取代基的类型及其位置有关。

This paper summarizes the research progress on glyeoglycerolipids involving their bioactivity and the relationship between structure and bioactivity. Glycoglycerolipids are important components of cell membranes and play an important role in cell biology. Glycoglycerolipids have various bioactivities, such as antioxidation, antiviral, antibacterial, anti - tumor, anti - inflammatory, anti - atherosclerosis and so on. The study of structure - activity relationship of glycoglycerolipids indicates that the activities are relative with acyl group, substituted group on the glycan and the location of them.