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β转化生长因子/smad信号通路与慢性移植肾肾病 被引量:6

β转化生长因子/smad信号通路与慢性移植肾肾病
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出处 《中华移植杂志(电子版)》 CAS 2009年第1期49-54,共6页 Chinese Journal of Transplantation(Electronic Edition)
关键词 转化生长因子-Β 肾病 慢性移植肾肾病 SMAD蛋白 Transforming growth factor beta Nephrosis Chronic allograft nephropathy Smad protein
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  • 1Schnaper HW, Hayashida T, Hubchak SC, et al. TGF-beta signal transduction and mesangial cell fibrogenesis. Am J Physiol Renal Physiol, 2003, 284(2) : F243-F252.
  • 2Poncelet AC, de Caestecker MP, Schnaper HW. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells. Kidney Int, 1999, 56(4) : 1354-1365.
  • 3Oldroyd SD, Thomas GL, Gabbiani G, et al. Interferon-gamma inhibits experimental renal fibrosis. Kidney Int, 1999, 56 ( 6 ) : 2116-2127.
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  • 5Strutz F, Heeg M, Kochsiek T, et al. Effect of pentoxifylline, pentifylline and gamma-interferon on proliferation, differention, and matrix synthesis of human renal fibroblasts. Nephrol Dial Transplant, 2000, 15 (10) : 1535-1546.
  • 6Shen H, Zhang M, Minuk GY, et al. Different effects of rat interferon alpha, beta and gamma on rat hepatic stellate cell proliferation and activation. BMC Cell Biol, 2002, 3:9.
  • 7Yamanaka O, Saika S, Okada Y, et al. Effects of interferongamma on human subconjunctival flbroblasts in the presence of TGFbeta1: reversal of TGFbeta-stimulated collagen production. Graefes Arch Clin Exp Ophthalmol, 2003, 241 (2) : 116-124.
  • 8Ulloa L, Doody J, Massague J. Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. Nature, 1999, 397(6721) :710-713.
  • 9Ghosh AK, Yuan W, Mori Y, et al. Antagonistic regulation of Type Ⅰ collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/ CBP transcriptional coactivators. J Biol Chem, 2001, 276(14) : 11041-11048.
  • 10Granstein RD, Flotte TJ, Amento EP. lnterferons and collagen production. J Invest Dermatol, 1990, 95(6 Suppl) :75S-80S.

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