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BMP转染骨髓间充质干细胞治疗骨缺损的研究进展

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摘要 骨缺损是指骨折断端因某种原因丧失了一些骨质而形成较大的缺损，多见于创伤、感染、先天性因素及肿瘤切除等。骨移植术是最常用的治疗手段，包括自体骨移植、异体骨甚至异种骨移植。自体骨移植虽具有较好的成骨活性，不存在免疫方面的问题，但需另作切口取骨，供骨来源受限，有供骨区疼痛、失血、手术瘢痕形成和时间延长等缺点；异体骨及异种骨移植难以及时获取移植骨，且有乙肝、爱滋病等感染及免疫反应的危险。
作者 向慧（综述） 覃佳强（审校）
机构地区 重庆医科大学附属儿童医院矫形外科
出处 《临床小儿外科杂志》 CAS 2009年第3期60-62,共3页 Journal of Clinical Pediatric Surgery
关键词 干细胞治疗 骨缺损 骨髓间充质 BMP 自体骨移植 异种骨移植 转染 免疫反应
分类号 R318.04 [医药卫生—生物医学工程] R683 [医药卫生—骨科学]
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参考文献22

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二级参考文献55

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临床小儿外科杂志
2009年 第3期

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