低温真空甲醛与过氧化氢等离子灭菌效果比较

Low-temperature Vacuum Formaldehyde and Hydrogen Peroxide Plasma Sterilization:An Effect Comparison

目的探讨低温真空甲醛的杀菌效果。方法试验组采用自研的140 L低温真空甲醛灭菌器灭菌;对照组采用"新华"牌过氧化氢等离子灭菌器灭菌,两组灭菌效果均采用生物指示剂监测。结果试验组运行的50次灭菌程序,生物指示剂全部被杀灭,灭菌合格率为100%;对照组运行30次灭菌程序,生物指示剂未被全部杀灭,只有8次灭菌合格,灭菌合格率26%,两组灭菌效果差异有统计学意义(P<0.05)。结论过氧化氢等离子灭菌穿透力稍差,对细长管道和器械腔隙的灭菌效果不可靠;低温真空甲醛灭菌穿透力强,能杀灭器械腔隙和细长管道内的所有微生物,适合对细长管道、多腔隙电动力器械、电子仪器和精密光学仪器的灭菌。

OBJECTIVE To explore the sterilizing effect of low-temperature vacuum formaldehyde. METHODS The test group used the own-produced 140 L low-temperature vacuum formaldehyde sterilizer for sterilization; and the control group used ＂ Xinhua＂ hydrogen peroxide plasma sterilizer. Sterilization effect of the two groups was monitored by biological indicator. RESULTS After 50 sterilization procedures run in test group, the biological indicators the bacterial were all killed, the qualification rate of sterilization was 100%. But after 30 sterilization procedures run in control group, only 8 procedures were qualified, the qualification rate of sterilization was 26%. The sterilizing effect of the two groups was significantly different （P〈0.05）. CONCLUSIONS The penetration power of hydrogen peroxide plasma sterilization is poor, sterilization effect on the slender pipes and devices lacunes are not reliable. The penetrating power of low-temperature vacuum formaldehyde sterilization is strong, it can kill all microorganisms in the slender tubes and devices lacunes. It is suitable for sterilization of the slender channel, multi-lacune devices, electronic appliances and precision optical instrument.