老年医院重症监护病房患者下呼吸道感染病原菌及耐药性的分析

Geriatric Hospital Pathogens of Lower Respiratory Tract Infection among Patients in ICU of a and Their Drug Resistance Analysis

目的探讨老年医院重症监护病房患者下呼吸道感染病原菌分布的特点及耐药情况。方法回顾性总结和分析医院2006年8月-2007年9月重症监护病房下呼吸道感染患者痰标本分离的111株病原菌及耐药性。结果98例感染者共分离出病原菌数111株,以革兰阴性杆菌为主,78株,占70.27%;革兰阴性杆菌中,铜绿假单胞菌位居第1位,23株,占20.72%;在革兰阳性杆菌中,除亚胺培南外,对其他抗菌药物耐药率较高,且表现多药耐药性。结论老年医院重症监护病房患者下呼吸道感染主要是以革兰阴性杆菌为主,病原菌显示多药耐药性,因此,临床应根据药敏结果科学合理地选择抗菌药物。

OBJECTIVE To explore the pathogen distribution and their resistance in ICU of Geriatric hospital. METHODS 111 strains isolated from lower respiratory tract were collected from Sep 2006 to August 2007. The antibiotic resistance were tested. RESULTS Among 111 strains, G- strains accounted for 70. 27%, in which Pseudomonas aeruginosa was the most common （20.72%）. The G＋ bacteria were multi-resistant to most of the antibiotics except impenem. CONCLUSIONS The most common pathogens in ICU of geriatric hospital is G- bacteria with multi-resistance. The Antibiotics should be selected reasonably.