肝功能衰竭合并水肿患者应用人血白蛋白

人血白蛋白是治疗肝硬化合并水肿的药物之一,在临床上应用广泛。但是当肝功能衰竭患者合并水肿时是否可以使用白蛋白,许多临床医生存在疑虑,担心诱发肝性脑病。我们综述了既往文献,从肝性脑病的发病机制和白蛋白代谢等方面进行分析,认为可以在肝功能衰竭患者合并水肿时应用白蛋白,但应监测人血白蛋白内的氨浓度。

The human serum albumin,one of drugs which can be used in patients of liver cirrhosis complicating with edema, has been widely used in the clinical practice. But when patients of hepatic failure are complicated with edema, many doctors suspect whether albumin can be used for edema. They are afraid that albumin could cause hepatic encephalopathy. We review the previous literatures.analyzing pathogenesis of hepatic encephalopathy, metabolism of albttmin and so on,and think that albumin can be used in patients of hepatic failure complicating with edema, but ammonia concentration in human serum albumin should be monitored.