Survivin在肾脏缺血再灌注损伤发生机制中的作用

目前的研究已表明,肾脏缺血再灌注损伤与细胞凋亡的发生密切相关。鉴于Survivin蛋白是凋亡抑制蛋白家族迄今为止发现的最强的凋亡抑制蛋白,本文将对Survivin在肾脏缺血再灌注损伤发生及发展的相关分子机制做一综述。

Survivin apoptosis inhibitory protein gene is a new member of the family,but also the strongest so far discovered inhibitor of apoptosis protein.The current study found that,Survivin and renal ischemia-reperfusion injury is closely related to the occurrence.In this paper,in recent years Survivin gene and renal ischemia-reperfusion injury studies were reviewed.