多发性硬化34例临床分析

目的探讨多发性硬化(MS)的临床特点。方法从一般临床资料、病变部位影像学等方面对MS进行分析。结果34例MS病例中,中青年女性多见,临床表现复杂。病程中多出现缓解复发,仅靠临床表现诊断较难,应结合磁共振成像、电生理、脑脊液检查等。糖皮质激素及免疫抑制剂治疗有效。结论根据临床表现,结合辅助检查可明显提高MS的确诊率。

Objective To study the clinical features of multiple sclerosis. Methods We have retrospectively studied the cases on general clinic, lesion locations, imaging. Results Among 34 MS cases, MS mainly affected young and middle-aged women, the clinical manifestations were complex. Alleviation and recurrence happened alternately during the course. Diagnosis was difficult based on clinical manifestations only. Combination of magnetic resonance imaging, electrophysiology and cerebrospinal fluid examination contribute to the diagnosis. Glucocorticoid treatment and immunosuppressive agents were effective. Conclusion According to clinical manifestations, it combined with examination may improve the diagnosis rate of MS.