司帕沙星与加替沙星治疗泌尿系统感染的成本-效果分析

目的比较司帕沙星与加替沙星治疗泌尿系统感染的经济效果。方法采用药物经济学原理对2种治疗方案进行成本-效果分析。结果司帕沙星组与加替沙星组治疗泌尿系统感染的有效率分别为90.9%、87.8%(P>0.05);成本-效果比(C/E)分别为0.67、0.32。与加替沙星组相比,司帕沙星组每增加一个单位效果需多花费10.70元。结论两组方案治疗泌尿系统感染的临床有效率、治愈率无显著性差异,但加替沙星组成本-效果比优于司帕沙星组。

Objective Compare the cost-effectiveness between sparfloxacin and gatifloxacin in the treatment of urinary system infection.Methods Principle of pharmacoeconomics were adopted to analyze cost--effectiveness of the 2 treatment schemes.Results The effective rates of sparfloxacin group and gatifloxacin group in the treatment of urinary system infection were 90.9% and 87.8% （P〉0.05） respectively; the cost-effectiveness ratio（C/ E） were 0.67 and 0.32 respectively.The cost for every one unit increment of effectiveness for sparfloxacin group was 10.70 yuan more than that of the gatifloxacin group.Conclusion There is no obvious difference between these two projects in clinical effective rate and cure rate of the treatment of urinary system infection,but cost-effectiveness ratio of the gatifloxacin group is superior to that of sparfloxacin group.