半胱氨酸天冬氨酸蛋白酶1和白细胞介素1β蛋白在不同遗传背景完全性葡萄胎中的表达
被引量:1
摘要
双亲来源的完全性葡萄胎(BiCHM)是完全性葡萄胎(CHM)中的一种独特类型,约占CHM的20%,与孤雄完全性葡萄胎(AnCHM;也称单亲来源的CHM)的基因起源和发病机制不同。BiCHM的两份染色体分别来自父母亲双方,而AnCHM的两份染色体均来自父亲。AnCHM常见于散发病例,患者其后正常妊娠的概率很高;而BiCHM常与家族性反复性葡萄胎(FRM)有关,患者一生中几乎无一次正常妊娠。
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2009年第9期703-704,共2页
Chinese Journal of Obstetrics and Gynecology
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