郑州市结核病人群中HIV感染调查

The status of HIV infection among TB patients in Zhengzhou

目的了解郑州地区结核病人群中HIV感染情况,为TB/HIV双重感染防治工作提供依据。方法采用连续抽样和关联保密的方法,对郑州地区7个结防机构2007年8月11日—11月31日就诊的活动性结核病人,用酶联免疫吸附试验（ELISA）进行HIV初筛,初筛阳性者做免疫印迹（western-blot）确认试验,并进行问卷调查。结果调查新登记结核病1583例,HIV阳性者9例,感染率0.6%;HIV感染病人年龄在13～60岁,男性组HIV感染率0.6%,女性组感染率为0.2%;不同年龄活动性结核病人中HIV感染者主要集中在青壮年,占88.9%;农村户口结核病人HIV感染率0.6%,城镇户口结核病人HIV感染率0.4%。固定人口HIV感染率0.7%,流动人口HIV感染率0.4%;HIV感染途径,采血浆、输入血液传播4例（44.4%）,异性传播2例（22.2%）;HIV阳性以新病人为多。涂片阳性。结论郑州地区结核病人群中HIV感染率0.6%;HIV阳性以新病人为主;结核病人群中HIV感染者主要集中在青壮年。

Objective To understand the state of HIV infection in patients of tuberculosis in Zhengzhou, and to provide evidence for TB/HIV co-infection control. Methods The primary screening of HIV infection was done by ELISA, those with positive result in primary screening were given final screening of HIV infection by WB and investigated by questionnaire. Results 1. The rate of HIV infection was 0. 6%（9 cases） in 1583 new tuberculosis patients. 2. HIV infection rate was 0.6% and 0. 2% in male and female in 13-60 years. TB/HIV patients were mainly young people, accounting for 88.9%. 3. HIV infection rate was 0.6% and 0. 43% for the patients registered in rural and urban area, 0.7% for permanent residents and 0.4% for migrant. 4. The transmission routes of HIV： 4 cases （44.4%） through transfusion, 2 cases （22.2%） through sexual contact. 5. New patients were main population with positive HIV. 6. The rates of HIV infection were 0.8% and 0.5% respectively in sputum smear positive and negative cases without statistic difference （P = 0.24〉 0.05）. Conclusions HIV infection rate in TB patients in Zhen Zhou is 0.6%; new patient is main population with positive HIV; the people of HIV infection in TB patients were mainly young adults.