2Mutchnick MG,Lindsay KL,Schiff ER,et al.Thymosin alpha-1 treatment of chronic hepatitis B:results of a phase Ⅲ multicentre,randomized,double-blind and placebo-controlled study[J].J Viral Hepat,1999,6 (5):397 -403.
3Andreone P,Cursaro C,Gramenzi A,et al.In vitro effect of thymosin-alphal and interferon-alpha on Th1 and Th2 cytokine synthesis in patients with chronic hepatitis C[J].J Viral Hepat,2001,8 (3):194-201.
4Zavaglia C,Severini R,Tinelli C,et al.A randomized,controlled study of thymosin-α1 therapy in patients with anti-HBe,HBV-DNA-positive chronic hepatitis B[J].Dig Dis Sci,2000,45 (4):690-696.
5Sugahara S,Ichida T,Yamagiwa S,et al.Thymosin-alpha 1 increases intrahepatic NKT cells and CTLs in patients with chronic hepatitis B[J].Hepatol Res,2002,24 (4):346-354.
7Saruc M,Ozden N,Turkel N,et al.Long-term outcomes of thymosin-alpha 1 and interferon alpha-2b combination therapy in patients with hepatitis Be antigen (HBeAg) negative chronichepatitis B[J].JPharmSci,2003,92 (7):1386-1395.
8You J,Zhuang L,Cheng HY,et al.A randomized,controlled,clinical study of thymosin alpha-1 versus interferon-alpha in patients with chronic hepatitis B lacking HBeAg in China[J].J Chin Med Assoc,2005,68 (2):65 -72.
9Mutchnick MG,Appelman HD,Chung HT,et al.Thymosin treatment of chronic hepatitis B:a place-controlled pilot trial[J].Hepatology.1991,14 (3):409-415.
10Lau GK.Use of immunomodulatory therapy (other than interferon) for the treatment of chronic hepatitis B virus infection[J].J Gastroenterol Hepatol,2000,15 (Suppl):E46-52.