摘要
结构生物学是以生物大分子的结构、运动和相互作用的研究为基础来阐明生命现象的科学,现已发展成为分子生物学的主流。它的研究内容包括生物大分子三维结构的测定以及与生物大分子发挥生物功能相伴随的动态的结构变化。生物学分支学科中的一些热点、重点都必然也必须在结构生物学研究的水平上得到最终的彻底的阐明,对生命本质认识的这种飞跃将带给人类一个崭新的世界。本文简要介绍结构生物学研究现状及发展。
The present study and develop of structural biology are briefly reviewed in this paper. Structural biology, which has been the backbone of molecular biology, clarifies life based on the study of the structures, movements and interactions of biomacromolecules. Structural biology consists of the measurements of the three dimensional structures of biomacromolecules and the structural changes while they function biologically. The hot and key points of this branch of biology must be completely and finally clarified on the level of structural biology.
出处
《中国科学基金》
CSCD
1998年第3期157-161,共5页
Bulletin of National Natural Science Foundation of China
关键词
结构生物学
蛋白质折叠
21世纪
生命科学
structural biology, folding of protein, denaturation, conformation, molecular design
