逆流色谱仪器装置的研究进展

Advances on the Apparatus of Counter-current Chromatography

逆流色谱是一种快速、高效、无固定相载体的新型液-液分配色谱技术。综述了高速逆流色谱、双向逆流色谱、正交轴逆流色谱、pH-区带精制逆流色谱及螺线型圆盘柱式逆流色谱仪器装置的研究进展,介绍了高速逆流色谱-质谱联用技术、高速逆流色谱-蒸发光散射联用技术、高速逆流色谱-高效液相色谱联用技术及二维逆流色谱技术的发展状况。

Counter-current chromatography is a kind of continuous liquid-liquid partition chromatographic technique with the unique feature of eliminating the use of a solid support. The development of high-speed counter-current chromatography,dual counter-current chromatography,cross-axis coil planet centrifuge,pH-zone-refining counter-current chromatography and spiral disk assembly counter-current chromatography were reviewed,and the latest progresses on high-speed counter-current chromatography coupled with mass spectrometry, evaporative light scattering detection, high-performance liquid chromatography and the two-dimensional counter-current chromatography were introduced.