摘要
大量文献报道,高迁移率族蛋白B1(HMGB1)在炎症性疾病的发病机理中发挥着重要的作用。近年来,对于HMGB1是否也参与了缺血再灌注介导的炎性损伤,引起了学者更为广泛的关注。本文就其在缺血再灌注损伤中的作用的研究进展进行了综述。
As is known, high mobility group box 1 （HMGB1） plays a crucial role in the etiopathogenesis of many inflammation diseases. In recent years, whether HMGB1 mediates inflammation caused by ischemic reperfusion injury or not, has provoked more and more attention. The aim of this paper is to summarize the research progress of the roles of HMGB1 in ischemia/reperfusion injury.
出处
《生命的化学》
CAS
CSCD
北大核心
2009年第5期658-661,共4页
Chemistry of Life
