食管癌三维适形放疗计划剂量学比较研究

Dosimetrical Comparison of Three Dimensional Conformal Radiation Therapy for Esophageal Carcinoma

目的:对比研究五野三维适形放疗(3DCRT)、三野3DCRT和常规模拟机定位放疗等3种不同方法在食管癌放射治疗中的优缺点。方法:20例食管癌患者采用3DCRT方法进行治疗,应用同一治疗计划系统,制定适形放疗和常规模拟机定位放疗方案,3种方案照射剂量均为1.8～2.0Gy/次,5次/周,50Gy/(5～6周)。结果:与常规模拟定位机定位放疗相比,食管癌照射中3DCRT有最好的剂量分布,既可明显提高靶区的剂量,同时能较好地保护正常组织。结论:食管癌的适形放疗技术能降低正常组织的放射损伤和并发症,提高放疗治疗的适形度,改善靶区的剂量分布。

Objectove To assess and compare the advantages and disadvantages of five fields of three dimensional eonformal radiation therapy（3DCRT）, three fields of 3DCRT and the simulator-guided radiation therapy for patients with esophageal earcinoma.Mothods Twenty patients with esophageal carcinoma were treated by three dimensional conformal radiation therapy,at the same TPS, three Dimensional conformal radiation therapy target and normal tissue of three radiotherapies were simulated.The treatment planning was five days per week with 1.8-2.0 Gy per fraction. 5 fractions per week,5OGy per 5-6 weeks. Rosults Compared with simulator-guided radiation therapy, 3DCRT planning has better dose distribution and protection of normal tissue. Conclusion Esophageal cancer conformal radiotherapy can reduce the radiation injury of the normal tissue and complications,and improve treatment of eonformal radiotherapy and the target dose distribution.[Ohinese Medical Equipment Journal, 2009,30 （9） ： 83-85]