150例继发性闭经患者的相关因素分析

The Analysis of Correlative Factor of Secondary Amenorrhea Patients Through 150 Cases

目的:总结当前社会环境条件下继发性闭经的发病背景、中医证型及与微量元素的联系等,为继发性闭经的诊治提供可靠的证候学依据,同时为今后防治该病提供可靠的科学依据。结果:(1)发病年龄20～29岁占54%;(2)工作类型无固定职业者占21.3%;(3)居住地多为城市;(4)65.3%饮食不节,或喜食辛辣香燥;(5)53.3%性格偏急躁或抑郁;(6)150例以下丘脑性闭经最多,主要的诱因有药物史(海洛因、避孕药等);(7)发微量元素钙、钡、镁、锌、铁、铝、铜均高于总体均数,锰低于总体均数,钾无统计学意义(P>0.05);(8)腰膝酸软出现频率最高的症状;(9)辨证结果为肝肾亏虚。结论:继发性闭经患者的发病多与饮食不节、情志不调、劳逸不畅及房劳等因素有关;存在着相关微量元素的平衡比例失调。与肝、脾、肾及痰湿瘀血关系最密切,以虚证或虚实夹杂为主,肾虚是致病关键。

Objective：The study aims at summarizing the secondary amenorrhea＇s background of invasion, syndrome of TCM and relation with trace element at the current social environment through the questionnaire of secondary amenorrhea patients＇data of 150 cases. Results： There are the invasion age of 54% patients between 20 and 29 years;2. There are 21.3% patients have no immobility type of work;3. Most of patients reside in city; 4. The patients that 65.3% patients have the habit of improper diet or preference for eating pungency fragrant and dry food;5. The character of 53.3% patients per to show temper or gloominess;6. Most of patients belong to hypothalamic amenorrhea in 150 eases, which the main inducements have drug history such as heroin ,oral contraceptive and so on;7. The data of trace element of hair,Cal- cium, Barium, Magnesium ,Zinc, Ferric, Aluminum and Cuprum are higher than the general average＇s and the data of Magnesium is lower than the general average＇s, the data of potassium have no statistical significance （ P 〉 0.05 ） ; 8. The highest frequency symptom is sore and limp loins and knees ;9. The result of differentiation is impairment of liver and kidney. Conclusion ： The invasion of secondary amenorrhea patients mainly relates to these elements such as improper diet, emotional disorder, upset of work and rest and excessive sexual intercourse and so on. There are imbalance of proportion of correlative trace element. It still has a close relationship with liver, spleen, kidney phlegm - damp and blood stasis. The manifestation have beth asthenia and deficiency interweaved with excess. Deficiency of kidney is the key of resulting in diseases.