肺癌术后肺感染的相关因素分析

The related factors of postoperative pulmonary infection in patients with lung cancer

目的:探讨肺癌患者术后发生肺感染的相关危险因素。方法:总结接受肺癌手术300例患者的临床资料,其中术后发生肺感染者27例,对其可能导致感染的各项因素进行统计分析。结果:单因素分析结果表明肺癌术后发生肺感染与合并慢性呼吸道疾病、手术时间、合并糖尿病、ICU入住时间、术后引流管留置时间等因素有关,而与年龄、术前肺功能水平、戒烟时限、术中失血量、吸烟量、机械通气时间、手术切除范围等因素无关;多因素分析表明合并慢性呼吸道疾病、ICU入住时间和术后引流管留置时间可能是术后肺感染的独立危险因素。结论:肺癌术后易发生肺部感染,但如能根据肺癌患者的特点,对各相关危险因素采取预防性治疗措施,可以减少肺部感染的发生。

Objective： To investigate related risk factors of postoperative pulmonary infection in patients with lung cancer. Methods： Clinical data of 300 patients with lung cancer were collected. 27 cases took place postoperative pulmonary infection, and the various factors statistical were analyzed. Results： Single-factor analysis showed that the occurrence of postoperative pulmonary infection was related to postoperative drainage stay time, operation time, with diabetes, ICU stay time and chronic respiratory disease;not related to smoking, the time limits on smoking cessation, pre-operative levels of lung function, blood loss, mechanical ventilation time and the scope of the surgery;multivariate analysis showed that with chronic respiratory diseases, postoperative drainage stay time, ICU stay time was the independent factor. Conclusion： Patients with lung cancer are susceptible to pulmonary infection, but the prevention for related factors maybe reduce the incidence of lung infection.