期刊文献+

赖诺普利对慢性心力衰竭患者血浆脑钠肽及左心室射血分数的影响

下载PDF
导出
摘要 目的:探讨赖诺普利对慢性心力衰竭患者血浆脑钠肽(BNP)及左心室射血分数(LVEF)的影响。方法:将慢性心力衰竭患者200例随机分为两组,赖诺普利组及对照组,两组均接受常规治疗,赖诺普利组加赖诺普利治疗,治疗前及治疗后6个月均测BNP及LVEF。结果:患者血浆BNP浓度明显下降(P<0.05),且与心衰程度相关,LVEF升高(P<0.05),与对照组比较差异有统计学意义(P<0.05)。结论:赖诺普利可使慢性心力衰竭患者血浆脑钠肽的浓度明显下降。
作者 刘清华
出处 《中国社区医师(医学专业)》 2009年第19期145-146,共2页
  • 相关文献

参考文献3

二级参考文献61

  • 1Sheth T,Parker T,Block A,et al.Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure[J].Am J Cardiol,2002,90(5):496-500.
  • 2Pimenta J,Pereira M,Castro A,et al.Neurohumoral activation,regulation of sodium excretion and vasodilator treatment in heart insufficiency[J].Rev Port Cardiol,2002,21(2):157-162.
  • 3van Veldhuisen DJ,Genth-Zotz S,Brouwer J,et al.High versus low-dose ACE inhibition in chronic heart failure:a double-blind,placebo-controlled study of imidapril[J].J Am Coll Cardiol,1998,32:1811-1818.
  • 4Inoko M,Fujita M,Nakae I,et al.Effect of angiotensin-converting enzyme inhibition on sympathetic tone in patients with mild to moderate heart failure[J].Jpn Circ J,2001,65(5):395-398.
  • 5Kinugawa T,Osaki S,Kato M,et al.Effects of angiotensin-converting enzyme inhibitor alacepril on exercise capacity and neurohormonal factors in patients with mild-to-moderate heart failure[J].Clin Exp Pharmacol Physiol,2002,29(12):1060-1065.
  • 6Kasama S,Toyama T,Kumakura H,et al.Effects of perindopril on cardiac sympathetic nerve activity in patients with congestive heart failure:comparison with enalapril[J].Eur J Nucl Med Mol Imaging,2005,[Epub ahead of print].
  • 7Yasumura Y,Miyatake K,Okamoto H,et al.Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin Ⅱ receptor blocker therapy in heart failure[J].Circ J,2004,68(4):361-366.
  • 8Hara Y,Hamada M,Shigematsu Y,et al.Effect of beta-blocker on left ventricular function and natriuretic peptides in patients with chronic heart failure treated with angiotensin-converting enzyme inhibitor[J].Jpn Circ J,2000,64(5):365-369.
  • 9Frantz RP,Olson LJ,Grill D,et al.Carvedilol therapy is associated with a sustained decline in brain natriuretic peptide levels in patients with congestive heart failure[J].Am Heart J,2005,149(3):541-547.
  • 10Takeda Y,Fukutomi T,Suzuki S,et al.Effects of carvedilol on plasma B-type natriuretic peptide concentration and symptoms in patients with heart failure and preserved ejection fraction[J].Am J Cardiol,2004,94(4):448-453.

共引文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部