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莪术油注射液对肝星状细胞凋亡的影响 被引量:2

Preliminary research on the mechanism of apoptosis hepatic stellate ceils induced by zedoary turmeric oil
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摘要 在各种治疗肝纤维化的方法中,以肝星状细胞(HSC)为靶点成为目前的研究热点。国艳等研究发现,莪术油注射液对体外培养的HSC有明显促凋亡作用,但其凋亡机制尚不清楚。我们进一步检测和证实了莪术油注射液对HSC的促凋亡作用;并同时检测促凋亡基因Fas、抑凋亡基因bcl-2与凋亡蛋白酶caspase-3,试图揭示莪术油注射液促进HSC凋亡作用的可能机制。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2009年第10期790-791,共2页 Chinese Journal of Hepatology
关键词 肝硬化 肝星状细胞 细胞凋亡 基因 BCL-2 莪术油 Liver cirrhosis Hepatic stellate cells Apoptosis Gene, bcl-2 Zedoary turmeric oil
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