期刊文献+

生酮饮食在神经系统疾病中的应用 被引量:4

下载PDF
导出
摘要 生酮饮食目前主要应用于顽固性癫痫的治疗,其治疗效果已得到大量临床资料的肯定,并激发起其临床及实验研究的高潮;而生酮饮食对其他神经系统疾病的作用也逐渐被重视,已进行的研究表明,生酮饮食或其代谢产物对帕金森病、阿尔茨海默病、脑缺血、缺氧、脑外伤等神经系统疾病均具有治疗作用,其机制涉及能量代谢、抗谷氨酸兴奋性毒性、抗氧化、抗凋亡、抗炎症等多重作用。
出处 《国际神经病学神经外科学杂志》 2009年第4期362-365,共4页 Journal of International Neurology and Neurosurgery
  • 相关文献

参考文献30

  • 1Kossoff EH. More fat and fewer seizures: dietary therapies for epilepsy. Lancet Neurol, 2004, 3(7) : 415-420.
  • 2Maalouf M, Rho JM, Mattson MP. The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev, 2009, 59(2): 293-315.
  • 3Marsh EB, Freeman JM, Kossoff EH, et al. The outcome of children with intractable seizures : a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year. Epilepsia, 2006, 47: 425-430.
  • 4Nordli Jr DR, Kuroda MM, Carroll J, et al. Experience with the ketogenie diet in infants. Pediatrics, 2001 , 108 : 129- 133.
  • 5Hemingway C, Freeman JM, Pillas DJ, et al. The ketogenic diet: a 3-6 year follow-up of 150 children enrolled prospectively. Pediatrics, 2001, 108: 898-905.
  • 6Ziegler DR, Oliveira DL, Pires C, et al. Ketogenic diet ted rats have low levels of S 100 B in cerebrospinal fluid. Neurosci Res, 2004, 50(4) : 375-379.
  • 7Xu XP, Sun RP, Jin RF. Effect of ketogenic diet on hippocampus synaptic reorganization and GluR5 , GluR6 mRNA in kainic acid induced model. Neurosci Bull, 2005, 21 (6): 418-424.
  • 8Vanitallie TB, Nonas C, Di Rocco A, et al. Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study. Neurology, 2005, 64: 728-730.
  • 9Tieu K, Perier C, Caspersen C, et al. D-b-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease. J Clin Invest, 2003 , 112 : 892-901.
  • 10Cheng B, Yang X, Hou Z, et al. D-beta-hydroxybutyrate inhibits the apoptosis of PC 12 cells induced by 6-OHDA in relation to up-regulating the ratio of Bcl-2/Bax mRNA. Auton Neurosci, 2007, 134: 38-44.

同被引文献29

引证文献4

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部