摘要
1,2-diiodo-3,3-dimethylbut-1-ene was synthesized used 3,3-dimethylbut-1-yne as the initial materials and Ce2(SO4)3 as catalyst in H2O.Then 5,5-dimethyl-1-(o-aminophenyl)-1,3-hexadiyne was synthesized from 1,2-diiodo-3,3-dimethylbut-1-ene and 2-ethynylaniline by cross-coupling rection in the presence of Pd(OAc)2 and CuI.The total yield was 68.7 %.The structure was characterized by NMR and MS spectrum.
1,2-diiodo-3,3-dimethylbut-1-ene was synthesized used 3,3-dimethylbut-1-yne as the initial materials and Ce2 （SO4 ）3 as catalyst in H2O. Then 5,5-dimethyl-l-（o-aminophenyl） -1,3-hexadiyne was synthesized from 1,2-diiodo-3,3-dimethylbut-1-ene and 2-ethynylaniline by cross-coupling rection in the presence of PS（OAc）2 and CuI. The total yield was 68.7 %. The structure was characterized by NMR and MS spectrum.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2009年第10期1443-1446,共4页
Chemical Research and Application
基金
湖南省自然科学基金资助项目(08JJ3018)
湖南省教育厅资助项目(08C828)
湘南学院资助项目(2007Y009)
