摘要
目的:分析幽门螺杆菌(Helicobacter Pylori,Hp)在青海高原地区回、藏、汉三个民族的感染状况以及与胃癌及各种胃炎性病变之间的关系分析。方法:分析我院连续10年内回、藏、汉三个民族被病理证实为胃癌及炎性病变的病理组织检查结果及Hp的感染状况。结果:Hp总阳性率为49.2%;回族54.8%,藏族49.8%,汉族44.5%,三者之间比较有非常显著性差异。各种炎性病变与胃癌之间的Hp阳性率比较有非常显著性差异。结论:Hp感染与民族、经济文化、饮食卫生等综合因素密切相关。Hp是慢性胃炎的重要致病因素,它与慢性炎症的程度以及肠化生和不典型增生等癌前病变的发生密切相关。
Objective： To assess the association between changes of gastritis and gastric cancer disease and helicobacter pylori （Hp） in Hui, Han and Tibetan population in Qinghai area. Methods： Eligible patients were 3 285 participants 15--82 years of age （male 1 819, female 1 466; mean age 42 years） from January 2000 to January 2009 in our hospital, whose diagnostic result was confirmed through endoscope, pathology and Hp test. The participants were included in Hui （n=990）, Han （n=1 370） and Tibetan （n= 958） population. The data was analyzed statistically. Results： Hp positive rate was 49. 2% （1 615 vs 3 285）,and the Hp positive rate of Hui, Han and Tibetan was 54. 8%, 44. 5% and 49. 5% respectively, the Hp positive rate had a significant difference among the three groups （P〈0.05）. And there was a significant difference in Hp positive rate between gastritis and gastric cancer. Conclusions：Infection of Hp is a risk factor of chronic gastritis, and Hp was associated with pre-cancer change in each ethnic group
出处
《高原医学杂志》
CAS
2009年第3期7-9,共3页
Journal of High Altitude Medicine
关键词
民族
高原
胃癌
胃炎
HP
Gastritis
Gastric cancer
Helicobacter pylori
Ethnic
