无创正压通气治疗在急性呼吸窘迫综合征中的应用价值

Treatment Effect of Noninvasive Positive Pressure Ventilation on Acute Respiratory Distress Syndrome

目的:探讨无创正压通气(NIPPV)治疗不同病因导致的急性呼吸窘迫综合征(ARDS)中的应用价值。方法:20例ARDS患者,分为原发性肺损伤组(9例)和继发性肺损伤组(11例),比较两组间的APACHEⅡ分值,NIPPV治疗前后动脉血pH值,氧合指数(PaO2/FiO2)、呼吸频率等。结果::两组治疗前与治疗2h后的PaO2/FiO2、呼吸频率均有显著差别,两组间的APACHEⅡ分值无显著性差别。结论:NIPPV治疗ARDS安全、有效,可以首选。

Objective：To investigate the effect of noninvasive positive pressure ventilation（NIPPV） on treatment of acute respiratory distress syndrome（ARDS）.Methods：According to the disease-induced factors,20 patients with ARDS were divided into the pulmonary factors group（n=9） and extra-pulmonary factors group（n=11）.The APACHEⅡ score,arterial pH,initial PaO2/FiO2,and respiratory rate in all patients were recorded and measured before and after treatment,and the results were compared between the both groups.Results：As compared between before and after 2h treatment with NIPPV in the two groups,There was a significant difference in initial PaO2∕FiO2,and respiratory rate,no difference in APACHEⅡ score between the both groups.Conclusions：NIPPV is safe and effective and can be used as the first choice for treatment of ARDS.