非酒精性脂肪性肝病96例临床诊断分析

Characteristic analysis of diagnosis on 96 eases of non-alcoholic fatty liver disease

目的探讨非酒精性脂肪性肝病（NAFLD）的临床诊断价值。方法回顾性分忻总结2001年6月至2008年6月诊治的96例非酒精性脂肪性肝病的临床资料。结果96例NAFLD患者有92例（95．83％）肝酶学异常，22例（22．92％）轻度胆红素增高，22例（22．92％）血脂异常。44例（47．83％）B超检查有脂肪肝的表现。22例肝活检病理学检查皆有不同程度的肝细胞脂肪病变和程度不同的小叶内炎症，部分病例有点状坏死和纤维化。结论非酒精性脂肪性肝病临床表现无特征性，而B超是最简单使用的诊断方法。

Objective To analyzed the clinical diagnostic characteristics of non-alcoholic fatty liver disease （NAFLD）. Methods The data of 96 cases of non-alcoholic fatty liver disease from June 2001 to June 2008 were retrospectively analyzed.Results There were 92 patients （95.83%） with liver enzymology abnormalities, 22 patients （22.92%） with mildly elevated bilirubin ; 22 patients （22.92%） with dyslipidemia, and 44 patients （47. 83%） with fatty liver detected by B-ultrasound. Detected by liver biopsy pathology, 22 cases showed that there were different degree liver fat lesions and lobular inflammation. Spotty necrosis and fibrosis were appeared in some of the cases. Conclusiion There were no typical diagnostic characteristics in non-alcoholic fatty liver disease. B-ultrasound is the simplest diagnostic method.