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蛋白质间相互作用检测方法的研究进展

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摘要 蛋白质是生命活动的基本功能单元,一切生理反应变化都离不开蛋白质以及蛋白质间的相互作用,人们不仅需要了解单个蛋白的结构及功能,更需要了解蛋白质组内部作用的功能过程,因此,了解蛋白一蛋白甚至蛋白一核酸相互作用的检测方法对于我们开展相关研究甚为重要。蛋白质相互作用分为3个方面:一是多亚基蛋白质的形成;二是多成分的蛋白复合体,如核孔复合体等;三是瞬时蛋白质相互作用。本文拟就蛋白质间相互作用检测方法的研究进展作一综述。
出处 《感染.炎症.修复》 2009年第3期183-186,共4页 Infection Inflammation Repair
基金 国家自然科学基金资助项目(30801187 30672178) 国家重点基础研究发展规划项目(2005CB522602)
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